| Date | Location | Result | |
| 03/05/10 | Wayne, NJ; Rec Center | DeSales 72, M.I.T. 64 | Box score |
| 02/27/10 | Cambridge, Mass. | Clark 71, M.I.T. 59 | Box score |
| 2/20/10 | Springfield, Mass. | M.I.T. 66, Springfield 62 | Box score |
| 2/17/10 | Emerson Gymnasium, Norton, Mass. | Wheaton 84, M.I.T. 77 | Box score |
| 02/13/10 | Cambridge, Mass. | M.I.T. 64, Coast Guard 53 | Box score |
| 02/11/10 | Cambridge, Mass. | M.I.T. 59, Clark 52 | Box score |
| 02/03/10 | Cambridge, Mass. | M.I.T. 67, Babson College 49 | Box score |
| 1/30/10 | Worcester, MA | M.I.T. 74, WPI 66 | Box score |
| 1/27/10 | New London, Conn. | M.I.T. 78, Coast Guard 58 | Box score |
| 01/23/10 | Cambridge, Mass. | Wheaton 60, M.I.T. 57 | Box score |
| 01/20/10 | Cambridge, Mass. | M.I.T. 67, Springfield 56 | Box score |
| 01/16/10 | Worcester, Mass. | M.I.T. 54, Clark 51 | Box score |
| 1/13/10 | Cambridge, Mass. (Rockwell Cage) | M.I.T. 76, WPI 53 | Box score |
| 01/09/10 | Babson Park, MA | M.I.T. 72, Babson College 45 | Box score |
| 1/5/10 | Medford, MA | M.I.T. 71, Tufts 59 | Box score |
| 12-28-09 | Cambridge, Mass. (Lavietes Pavilion) | Harvard 88, M.I.T. 61 | Box score |
| 12/12/09 | Cambridge, Mass. | M.I.T. 88, Lesley University 61 | Box score |
| 12/10/09 | Cambridge, Mass. | M.I.T. 98, Salem State 93 | Box score |
| 12/8/09 | BOSTON, MA - Clark Athletic Center | M.I.T. 74, UMass Boston 54 | Box score |
| 12/05/09 | Cambridge, Mass. | M.I.T. 78, Gordon College 73 | Box score |
| 12/03/09 | Hellenic College Brookline, MA | M.I.T. 76, Newbury College 50 | Box score |
| 12/01/09 | Brown & Plofker Gym, Boston, Mass. | M.I.T. 66, Emerson 51 | Box score |
| 11/28/09 | Cambridge, Mass. | M.I.T. 85, Suffolk 50 | Box score |
| 11/24/09 | Milton, Mass. | M.I.T. 66, Curry 56 | Box score |
| 11/21/09 | East Campus Arena | M.I.T. 56, Rensselaer 55 | Box score |
| 11/20/09 | East Campus Arena | M.I.T. 78, John Abbott 38 | Box score |
| 11/17/09 | Jean Yawkey Center - Boston, Mass. | M.I.T. 68, Emmanuel College 54 | Box score |